SCOPe 2.04: Domain d4ny8a3: 4ny8 A:149-335

Lineage for d4ny8a3 (4ny8 A:149-335)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase beta, catalytic (31 kD) fragment [81578] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81574] (143 PDB entries)
   Uniprot P06746

8. Domain d4ny8a3: 4ny8 A:149-335 [257200]
   Other proteins in same PDB: d4ny8a1, d4ny8a2
   automated match to d4klia3
   protein/DNA complex; complexed with 0kx, mn, na

Details for d4ny8a3

PDB Entry: 4ny8, 2.25 Å

PDB Description: DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site

PDB Compounds: (A:) DNA polymerase beta

SCOPe Domain Sequences for d4ny8a3:

Sequence, based on SEQRES records:

>d4ny8a3 d.218.1.2 (A:149-335) DNA polymerase beta, catalytic (31 kD) fragment {Human (Homo sapiens) [TaxId: 9606]}
ripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdmdvllthpsftsestkqp
kllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndekeyphrridirlipkdqyycg
vlyftgsdifnknmrahalekgftineytirplgvtgvageplpvdsekdifdyiqwkyr
epkdrse

Sequence, based on observed residues (ATOM records):

>d4ny8a3 d.218.1.2 (A:149-335) DNA polymerase beta, catalytic (31 kD) fragment {Human (Homo sapiens) [TaxId: 9606]}
ripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdmdvllthpsftsesqpkl
lhqvveqlqkvhfitdtlskgetkfmgvcqlpskndekeyphrridirlipkdqyycgvl
yftgsdifnknmrahalekgftineytirplgvtgvageplpvdsekdifdyiqwkyrep
kdrse

Timeline for d4ny8a3:

• d4ny8a3 is new in SCOPe 2.04-stable
  
• d4ny8a3 appears in SCOPe 2.05
  
• d4ny8a3 appears in the current release, SCOPe 2.08