SCOPe 2.07: Domain d4klca_: 4klc A:

Lineage for d4klca_ (4klc A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.92: Chelatase-like [53799] (3 superfamilies)
   duplication: tandem repeat of two domains; 3 layers (a/b/a); parallel beta-sheet of 4 strands, order 2134

4. Superfamily c.92.1: Chelatase [53800] (4 families)
   interdomain linker is short; swapping of C-terminal helices between the two domains

5. Family c.92.1.1: Ferrochelatase [53801] (2 protein domains)
   automatically mapped to Pfam PF00762

6. Protein Ferrochelatase [53802] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [64189] (21 PDB entries)

8. Domain d4klca_: 4klc A: [256870]
   automated match to d3aqia_
   complexed with fes, gol, hem; mutant

Details for d4klca_

PDB Entry: 4klc, 2.4 Å

PDB Description: E343D/F110A Double mutant of human ferrochelatase

PDB Compounds: (A:) Ferrochelatase, mitochondrial

SCOPe Domain Sequences for d4klca_:

Sequence; same for both SEQRES and ATOM records:

>d4klca_ c.92.1.1 (A:) Ferrochelatase {Human (Homo sapiens) [TaxId: 9606]}
rkpktgilmlnmggpetlgdvhdfllrlfldrdlmtlpiqnklapaiakrrtpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadhilke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdhidtlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql

Timeline for d4klca_:

• d4klca_ first appeared in SCOPe 2.04
  
• d4klca_ appears in SCOPe 2.06