SCOPe 2.05: Domain d4k7aa_: 4k7a A:

Lineage for d4k7aa_ (4k7a A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (50 PDB entries)
   Uniprot P10275 671-919

8. Domain d4k7aa_: 4k7a A: [256843]
   automated match to d2pnua_
   complexed with dht, mxd

Details for d4k7aa_

PDB Entry: 4k7a, 2.44 Å

PDB Description: Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d4k7aa_:

Sequence, based on SEQRES records:

>d4k7aa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfht

Sequence, based on observed residues (ATOM records):

>d4k7aa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiascsrrf
yqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyf
ht

Timeline for d4k7aa_:

• d4k7aa_ first appeared in SCOPe 2.04
  
• d4k7aa_ appears in SCOPe 2.06
  
• d4k7aa_ appears in the current release, SCOPe 2.08