Lineage for d4cv2a_ (4cv2 A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

    has additional subdomain(s) that are not in the common domain
  6. 2842913Protein automated matches [190085] (59 species)
    not a true protein
  7. 2843120Species Escherichia coli [TaxId:469008] [256724] (3 PDB entries)
  8. 2843121Domain d4cv2a_: 4cv2 A: [256725]
    automated match to d1qg6a_
    complexed with nai, pt6

Details for d4cv2a_

PDB Entry: 4cv2 (more details), 1.8 Å

PDB Description: Crystal structure of E. coli FabI in complex with NADH and CG400549
PDB Compounds: (A:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d4cv2a_:

Sequence, based on SEQRES records: (download)

>d4cv2a_ c.2.1.2 (A:) automated matches {Escherichia coli [TaxId: 469008]}
gflsgkrilvtgvasklsiaygiaqamhregaelaftyqndklkgrveefaaqlgsdivl
qcdvaedasidtmfaelgkvwpkfdgfvhsigfapgdqldgdyvnavtregfkiahdiss
ysfvamakacrsmlnpgsalltlsylgaeraipnynvmglakasleanvrymanamgpeg
vrvnaisagpirtlaasgikdfrkmlahceavtpirrtvtiedvgnsaaflcsdlsagis
gevvhvdggfsiaamn

Sequence, based on observed residues (ATOM records): (download)

>d4cv2a_ c.2.1.2 (A:) automated matches {Escherichia coli [TaxId: 469008]}
gflsgkrilvtgvasklsiaygiaqamhregaelaftyqndklkgrveefaaqlgsdivl
qcdvaedasidtmfaelgkvwpkfdgfvhsigfapgdqldgdyvnavtregfkiahdiss
ysfvamakacrsmlnpgsalltlsylgaeraipnynvmglakasleanvrymanamgpeg
vrvnaisagpiavtpirrtvtiedvgnsaaflcsdlsagisgevvhvdggfsiaamn

SCOPe Domain Coordinates for d4cv2a_:

Click to download the PDB-style file with coordinates for d4cv2a_.
(The format of our PDB-style files is described here.)

Timeline for d4cv2a_: