SCOPe 2.05: Domain d4csja_: 4csj A:

Lineage for d4csja_ (4csj A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (138 PDB entries)

8. Domain d4csja_: 4csj A: [256689]
   automated match to d3mnea_
   complexed with edo, nn7

Details for d4csja_

PDB Entry: 4csj, 2.3 Å

PDB Description: The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation

PDB Compounds: (A:) Glucocorticoid receptor

SCOPe Domain Sequences for d4csja_:

Sequence; same for both SEQRES and ATOM records:

>d4csja_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptlvslleviepevlyagydssvpdstwrimttlnmlggrqmiaavkwakaipgfrnlhl
ddqmtllqyswmslmafalgwrsyrqssanllcfapdliineqrmtlpdmydqckhmlyv
sselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkregnss
qnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysngni
kkllfhq

Timeline for d4csja_:

• d4csja_ first appeared in SCOPe 2.04
  
• d4csja_ appears in SCOPe 2.06
  
• d4csja_ appears in the current release, SCOPe 2.08