SCOPe 2.05: Domain d4ckua_: 4cku A:

Lineage for d4ckua_ (4cku A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species)

7. Species Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (22 PDB entries)

8. Domain d4ckua_: 4cku A: [256625]
   automated match to d1leea_
   complexed with p2f

Details for d4ckua_

PDB Entry: 4cku, 1.85 Å

PDB Description: three dimensional structure of plasmepsin ii in complex with hydroxyethylamine-based inhibitor

PDB Compounds: (A:) Plasmepsin-2

SCOPe Domain Sequences for d4ckua_:

Sequence, based on SEQRES records:

>d4ckua_ b.50.1.2 (A:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II [TaxId: 5833]}
ndnielvdfqnimfygdaevgdnqqpftfildtgsanlwvpsvkcttagcltkhlydssk
srtyekdgtkvemnyvsgtvsgffskdlvtvgnlslpykfievidtngfeptytastfdg
ilglgwkdlsigsvdpivvelknqnkienalftfylpvhdkhtgfltiggieerfyegpl
tyeklnhdlywqitldahvgnislekancivdsgtsaitvptdflnkmlqnldvikvpfl
pfyvtlcnnsklptfeftsengkytlepeyylqhiedvgpglcmlniigldfpvptfilg
dpfmrkyftvfdydnhsvgialakknl

Sequence, based on observed residues (ATOM records):

>d4ckua_ b.50.1.2 (A:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II [TaxId: 5833]}
ndnielvdfqnimfygdaevgdnqqpftfildtgsanlwvpsvkcttagcltkhlydssk
srtyekdgtkvemnyvsgtvsgffskdlvtvgnlslpykfievidtngfeptytastfdg
ilglgwkdlsigsvdpivvelknqnkienalftfylpvhdkhtgfltiggieerfyegpl
tyeklnhdlywqitldahvgnislekancivdsgtsaitvptdflnkmlqnldvikvpfl
pfyvtlcnnsklptfeftsengkytlepeyylqhipglcmlniigldfpvptfilgdpfm
rkyftvfdydnhsvgialakknl

Timeline for d4ckua_:

• d4ckua_ first appeared in SCOPe 2.04
  
• d4ckua_ appears in SCOPe 2.06
  
• d4ckua_ appears in the current release, SCOPe 2.08