SCOPe 2.06: Domain d2ilaa_: 2ila A:

Lineage for d2ilaa_ (2ila A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 proteins)

6. Protein Interleukin-1alpha [50368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50369] (1 PDB entry)

8. Domain d2ilaa_: 2ila A: [25560]
   CA-atoms only

Details for d2ilaa_

PDB Entry: 2ila, 2.3 Å

PDB Description: structure of interleukin 1alpha at 2.7-angstroms resolution

PDB Compounds: (A:) interleukin-1 alpha

SCOPe Domain Sequences for d2ilaa_:

Sequence, based on SEQRES records:

>d2ilaa_ b.42.1.2 (A:) Interleukin-1alpha {Human (Homo sapiens) [TaxId: 9606]}
nvkynfmriikyefilndalnqsiiranaqyltaaalhnldeavkfdmgayksskddaki
tvilrisktqlyvtaqdedqpvllkempeipktitgsetnllffwethgtknyftsvahp
nlfiatkqdywvclaggppsitdfqile

Sequence, based on observed residues (ATOM records):

>d2ilaa_ b.42.1.2 (A:) Interleukin-1alpha {Human (Homo sapiens) [TaxId: 9606]}
nvkynfmriikyefilndalnqsiiranaqyltaaalhnldeavkfdmgaykssakitvi
lrisktqlyvtaqdedqpvllkempeipktitgsetnllffwethgtknyftsvahpnlf
iatkqdywvclaggppsitdfqile

Timeline for d2ilaa_:

• d2ilaa_ first appeared (with stable ids) in SCOP 1.55, called d2ila__
  
• d2ilaa_ appears in SCOPe 2.05
  
• d2ilaa_ appears in SCOPe 2.07
  
• d2ilaa_ appears in the current release, SCOPe 2.08