SCOPe 2.05: Family b.82.2.14: Histone demethylase core

Lineage for Family b.82.2.14: Histone demethylase core

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families)
   Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold

5. Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
   Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801

Proteins:

1. JHDM2B core [254344] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254777] (1 PDB entry)

2. JMJD2A core [254342] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254775] (23 PDB entries)

3. JMJD2D core [254343] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254776] (2 PDB entries)

4. automated matches [254635] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [255633] (14 PDB entries)

More info for Family b.82.2.14: Histone demethylase core

Timeline for Family b.82.2.14: Histone demethylase core:

• Family b.82.2.14: Histone demethylase core first appeared in SCOPe 2.04
  
• Family b.82.2.14: Histone demethylase core appears in SCOPe 2.06
  
• Family b.82.2.14: Histone demethylase core appears in the current release, SCOPe 2.08, called Family b.82.2.14: Jumonji domain / Histone demethylase core