Lineage for d4nwla1 (4nwl A:-10-182)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2387558Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2387559Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2389767Family b.47.1.3: Viral proteases [50596] (5 protein domains)
    beta sheet in the first domain is opened rather than forms a barrel
  6. 2389857Protein automated matches [190658] (7 species)
    not a true protein
  7. 2389866Species Hepatitis C virus subtype 1a [TaxId:31646] [226463] (20 PDB entries)
  8. 2389885Domain d4nwla1: 4nwl A:-10-182 [254029]
    Other proteins in same PDB: d4nwla2, d4nwlb2
    automated match to d4nwka_
    complexed with 2r9, zn

Details for d4nwla1

PDB Entry: 4nwl (more details), 2.2 Å

PDB Description: crystal structure of hepatis c virus protease (ns3) complexed with bms-650032 aka n-(tert-butoxycarbonyl)-3-me thyl-l-valyl-(4r)-4-((7- chloro-4-methoxy-1-isoquinolinyl)o xy)-n-((1r,2s)-1- ((cyclopropylsulfonyl)carbamoyl)-2-vinylc yclopropyl)-l-prolinamide
PDB Compounds: (A:) HCV NS3 1a Protease

SCOPe Domain Sequences for d4nwla1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4nwla1 b.47.1.3 (A:-10-182) automated matches {Hepatitis C virus subtype 1a [TaxId: 31646]}

SCOPe Domain Coordinates for d4nwla1:

Click to download the PDB-style file with coordinates for d4nwla1.
(The format of our PDB-style files is described here.)

Timeline for d4nwla1:

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Domains from same chain:
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