Lineage for d4k8va2 (4k8v A:394-507)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2013910Fold a.160: PAP/OAS1 substrate-binding domain [81632] (1 superfamily)
    core: 5-helical bundle; up-and-down; right-handed twist
  4. 2013911Superfamily a.160.1: PAP/OAS1 substrate-binding domain [81631] (7 families) (S)
    this domain follows the catalytic nucleotidyltransferase domain
  5. 2013982Family a.160.1.6: cGAMP synthase, cGAS C-terminal domain [254175] (1 protein)
    PubMed 23647843; structurally very similar to hOAS1 (a.160.1.2)
  6. 2013983Protein cGAMP synthase, cGAS C-terminal domain [254395] (2 species)
  7. 2013984Species Mouse (Mus musculus) [TaxId:10090] [254831] (1 PDB entry)
  8. 2013985Domain d4k8va2: 4k8v A:394-507 [253166]
    Other proteins in same PDB: d4k8va1, d4k8va3, d4k8vb1, d4k8vb3, d4k8vc1, d4k8vc3, d4k8vd1, d4k8vd3
    complexed with zn

Details for d4k8va2

PDB Entry: 4k8v (more details), 2 Å

PDB Description: Structure of cyclic GMP-AMP Synthase (cGAS)
PDB Compounds: (A:) Cyclic GMP-AMP synthase

SCOPe Domain Sequences for d4k8va2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4k8va2 a.160.1.6 (A:394-507) cGAMP synthase, cGAS C-terminal domain {Mouse (Mus musculus) [TaxId: 10090]}

SCOPe Domain Coordinates for d4k8va2:

Click to download the PDB-style file with coordinates for d4k8va2.
(The format of our PDB-style files is described here.)

Timeline for d4k8va2: