SCOPe 2.08: Domain d4jq3b_: 4jq3 B:

Lineage for d4jq3b_ (4jq3 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)

7. Species Human (Homo sapiens), type III [TaxId:9606] [69383] (16 PDB entries)
   bile acid binding protein

8. Domain d4jq3b_: 4jq3 B: [253002]
   automated match to d4jqab_
   complexed with edo, nap, po4, tla, zom

Details for d4jq3b_

PDB Entry: 4jq3, 1.75 Å

PDB Description: AKR1C2 complex with zomepirac

PDB Compounds: (B:) Aldo-keto reductase family 1 member C2

SCOPe Domain Sequences for d4jq3b_:

Sequence; same for both SEQRES and ATOM records:

>d4jq3b_ c.1.7.1 (B:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}
skyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeqvg
lairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpvsv
kpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkpgl
kykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpvlc
alakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidglnrn
vryltldifagppnypfs

Timeline for d4jq3b_:

• d4jq3b_ first appeared in SCOPe 2.04
  
• d4jq3b_ appears in SCOPe 2.07