Lineage for d4jlka_ (4jlk A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2446887Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2446888Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2446889Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145
  6. 2446980Protein Deoxycytidine kinase [89657] (1 species)
  7. 2446981Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)
  8. 2447014Domain d4jlka_: 4jlk A: [252968]
    automated match to d1p60a_
    complexed with 1no, udp; mutant

Details for d4jlka_

PDB Entry: 4jlk (more details), 1.89 Å

PDB Description: human dck c4s-s74e mutant in complex with udp and the f2.2.1 inhibitor (2-[({2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine)
PDB Compounds: (A:) Deoxycytidine kinase

SCOPe Domain Sequences for d4jlka_:

Sequence, based on SEQRES records: (download)

>d4jlka_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4jlka_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4jlka_:

Click to download the PDB-style file with coordinates for d4jlka_.
(The format of our PDB-style files is described here.)

Timeline for d4jlka_: