SCOPe 2.07: Domain d4hwya_: 4hwy A:

Lineage for d4hwya_ (4hwy A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.0: automated matches [191342] (1 protein)
   not a true family

6. Protein automated matches [190230] (21 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [256293] (1 PDB entry)

8. Domain d4hwya_: 4hwy A: [252534]
   automated match to d3pbha_
   complexed with bma, nag

Details for d4hwya_

PDB Entry: 4hwy, 2.1 Å

PDB Description: trypanosoma brucei procathepsin b solved from 40 fs free-electron laser pulse data by serial femtosecond x-ray crystallography

PDB Compounds: (A:) Cysteine peptidase C (CPC)

SCOPe Domain Sequences for d4hwya_:

Sequence, based on SEQRES records:

>d4hwya_ d.3.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 999953]}
edapvlskafvdrvnrlnrgiwkakydgvmqnitlreakrlngvikknnnasilpkrrft
eeearaplpssfdsaeawpncptipqiadqsacgscwavaaasamsdrfctmggvqdvhi
sagdllaccsdcgdgcnggdpdrawayfsstglvsdycqpypfphcshhskskngyppcs
qfnfdtpkcnytcddptipvvnyrswtsyalqgeddymrelffrgpfevafdvyedfiay
nsgvyhhvsgqylgghavrlvgwgtsngvpywkianswntewgmdgyflirrgssecgie
dggsagiplapnta

Sequence, based on observed residues (ATOM records):

>d4hwya_ d.3.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 999953]}
edapvlskafvdrvnrlnrgiwkakydgvmqnitlreakrlngvikilpkrrfteeeara
plpssfdsaeawpncptipqiadqsacgscwavaaasamsdrfctmggvqdvhisagdll
accsdcgdgcnggdpdrawayfsstglvsdycqpypfphcshhskskngyppcsqfnfdt
pkcnytcddptipvvnyrswtsyalqgeddymrelffrgpfevafdvyedfiaynsgvyh
hvsgqylgghavrlvgwgtsngvpywkianswntewgmdgyflirrgssecgiedggsag
iplapnta

Timeline for d4hwya_:

• d4hwya_ first appeared in SCOPe 2.04
  
• d4hwya_ appears in SCOPe 2.06