SCOPe 2.08: Domain d4hsic_: 4hsi C:

Lineage for d4hsic_ (4hsi C:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.76: Viral glycoprotein ectodomain-like [161007] (1 superfamily)
   complex fold; contains three rigid, mostly-beta domains and an alpha-helical region, acting as a conformatiomal switch ("fusion stalk")

4. Superfamily e.76.1: Viral glycoprotein ectodomain-like [161008] (3 families)

5. Family e.76.1.1: Glycoprotein B-like [161009] (1 protein)
   Pfam PF00606; Herpesvirus Glycoprotein B

6. Protein Glycoprotein B [161010] (1 species)

7. Species Human herpesvirus 1 [TaxId:10298] [161011] (7 PDB entries)
   Uniprot P06437 111-725

8. Domain d4hsic_: 4hsi C: [252499]
   automated match to d2gumb_
   complexed with cl, mry, nag; mutant

Details for d4hsic_

PDB Entry: 4hsi, 3.1 Å

PDB Description: glycoprotein b from herpes simplex virus type 1, a504p/r505g/q507g/n511g mutant, low-ph

PDB Compounds: (C:) Envelope glycoprotein B

SCOPe Domain Sequences for d4hsic_:

Sequence, based on SEQRES records:

>d4hsic_ e.76.1.1 (C:) Glycoprotein B {Human herpesvirus 1 [TaxId: 10298]}
kaentdanfyvcppptgatvvqfeqprrcptrpegqnytegiavvfkeniapykfkatmy
ykdvtvsqvwfghrysqfmgifedrapvpfeevidkinakgvcrstakyvrnnlettafh
rddhetdmelkpanaatrtsrgwhttdlkynpsrveafhrygttvnciveevdarsvypy
defvlatgdfvymspfygyregshtehtsyaadrfkqvdgfyardlttkaratapttrnl
lttpkftvawdwvpkrpsvctmtkwqevdemlrseyggsfrfssdaisttfttnlteypl
srvdlgdcigkdardamdrifarrynathikvgqpqyylanggfliayqpllsntlaely
vrehlreqsrkppnptppppgasanasverikttssiefpglgftyghiqrhvndmlgrv
aiawcelqnheltlwnearklnpnaiasvtvgrrvsarmlgdvmavstcvpvaadnvivq
nsmrissrpgacysrplvsfryedqgplvegqlgennelrltrdaiepctvghrryftfg
ggyvyfeeyayshqlsradittvstfidlnitmledhefvplevytrheikdsglldyte
vqrrnqlhdlrfadidtvih

Sequence, based on observed residues (ATOM records):

>d4hsic_ e.76.1.1 (C:) Glycoprotein B {Human herpesvirus 1 [TaxId: 10298]}
kaentdanfyvcppptgatvvqfeqprrcptrpegqnytegiavvfkeniapykfkatmy
ykdvtvsqvwfghrysqfmgifedrapvpfeevidkinakgvcrstakyvrnnlettafh
rddhetdmelkpanaatrtsrgwhttdlkynpsrveafhrygttvnciveevdarsvypy
defvlatgdfvymspfygyregshtehtsyaadrfkqvdgfyardlttkaratapttrnl
lttpkftvawdwvpkrpsvctmtkwqevdemlrseyggsfrfssdaisttfttnlteypl
srvdlgdcigkdardamdrifarrynathikvgqpqyylanggfliayqpllsntlaely
vrehlreqsverikttssiefpglgftyghiqrhvndmlgrvaiawcelqnheltlwnea
rklnpnaiasvtvgrrvsarmlgdvmavstcvpvaadnvivqnsmrissrpgacysrplv
sfryedqgplvegqlgennelrltrdaiepctvghrryftfgggyvyfeeyayshqlsra
dittvstfidlnitmledhefvplevytrheikdsglldytevqrrnqlhdlrfadidtv
ih

Timeline for d4hsic_:

• d4hsic_ first appeared in SCOPe 2.04
  
• d4hsic_ appears in SCOPe 2.07