SCOPe 2.05: Domain d4hqra_: 4hqr A:

Lineage for d4hqra_ (4hqr A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein automated matches [190398] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187267] (13 PDB entries)

8. Domain d4hqra_: 4hqr A: [252485]
   automated match to d1gqfa_
   mutant

Details for d4hqra_

PDB Entry: 4hqr, 3 Å

PDB Description: Crystal Structure of mutant form of Caspase-7

PDB Compounds: (A:) caspase-7

SCOPe Domain Sequences for d4hqra_:

Sequence, based on SEQRES records:

>d4hqra_ c.17.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktlle
kpklffiqacrgtelddgiqaasgpindlvprgstdanprykipveadflfaystvpgyy
swrspgrgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhekkqipc
vvsmltkelyfsq

Sequence, based on observed residues (ATOM records):

>d4hqra_ c.17.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktlle
kpklffiqacrgtelykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkd
leimqiltrvndrvarhfekqipcvvsmltkelyfsq

Timeline for d4hqra_:

• d4hqra_ first appeared in SCOPe 2.04
  
• d4hqra_ appears in SCOPe 2.06
  
• d4hqra_ appears in the current release, SCOPe 2.08