SCOPe 2.08: Domain d4hq0b_: 4hq0 B:

Lineage for d4hq0b_ (4hq0 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-7 [63961] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63962] (12 PDB entries)
   Uniprot P55210 57-303

8. Domain d4hq0b_: 4hq0 B: [252484]
   automated match to d1gqfa_
   mutant

Details for d4hq0b_

PDB Entry: 4hq0, 3 Å

PDB Description: Crystal Structure of mutant form of Caspase-7

PDB Compounds: (B:) caspase-7

SCOPe Domain Sequences for d4hq0b_:

Sequence, based on SEQRES records:

>d4hq0b_ c.17.1.1 (B:) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
rdrvptyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivy
ndcscakmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrc
ktllekpklffiqacrgtelddgiqaasgpindlvprgstdanprykipveadflfayst
vpgyyswrspgrgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhek
kqipcvvsmltkelyfsq

Sequence, based on observed residues (ATOM records):

>d4hq0b_ c.17.1.1 (B:) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
rdrvptyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivy
ndcscakmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrc
ktllekpklffiqacrprykipveadflfaystvpgyyswrspgrgswfvqalcsileeh
gkdleimqiltrvndrvarhqipcvvsmltkelyfsq

Timeline for d4hq0b_:

• d4hq0b_ first appeared in SCOPe 2.04
  
• d4hq0b_ appears in SCOPe 2.07