SCOPe 2.04: Domain d4hooa_: 4hoo A:

Lineage for d4hooa_ (4hoo A:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families)
   Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold

5. Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
   Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801

6. Protein JMJD2D core [254343] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254776] (2 PDB entries)

8. Domain d4hooa_: 4hoo A: [252476]
   automated match to d3dxua_
   complexed with act, ni, zn

Details for d4hooa_

PDB Entry: 4hoo, 2.5 Å

PDB Description: crystal structure of human jmjd2d/kdm4d apoenzyme

PDB Compounds: (A:) Lysine-specific demethylase 4D

SCOPe Domain Sequences for d4hooa_:

Sequence, based on SEQRES records:

>d4hooa_ b.82.2.14 (A:) JMJD2D core {Human (Homo sapiens) [TaxId: 9606]}
qnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkaretydniseili
atplqqvasgragvftqyhkkaaamtvgeyrhlanskkyqtpphqnfedlerkywknriy
nspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpylyfgmwkttfaw
htedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcgaflrhkvalisp
tvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprwidygkmasqcs
cgearvtfsmdafvrilqperydlwkrgqd

Sequence, based on observed residues (ATOM records):

>d4hooa_ b.82.2.14 (A:) JMJD2D core {Human (Homo sapiens) [TaxId: 9606]}
qnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkaretydniseili
atplqqvasgragvftqyhkkaaamtvgeyrhlanskkyqtpphqnfedlerkywknriy
nspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpylyfgmwkttfaw
htedmdlysinylhlgepktwyvvppehgqrlerlarelfpgscgaflrhkvalisptvl
kengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprwidygkmasqcscge
arvtfsmdafvrilqperydlwkrgqd

Timeline for d4hooa_:

• d4hooa_ is new in SCOPe 2.04-stable
  
• d4hooa_ appears in SCOPe 2.05
  
• d4hooa_ appears in the current release, SCOPe 2.08