Lineage for d4hf4b_ (4hf4 B:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342564Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2342565Protein automated matches [190983] (9 species)
    not a true protein
  7. 2342579Species Human (Homo sapiens) [TaxId:9606] [188676] (122 PDB entries)
  8. 2342611Domain d4hf4b_: 4hf4 B: [252423]
    automated match to d4heua_
    complexed with 15h, gol, so4, zn

Details for d4hf4b_

PDB Entry: 4hf4 (more details), 2 Å

PDB Description: Crystal Structure of PDE10A with a biaryl ether inhibitor (1-(1-(3-(4-(benzo[d]thiazol-2-ylamino)phenoxy)pyrazin-2-yl)piperidin-4-yl)ethanol)
PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4hf4b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4hf4b_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4hf4b_:

Click to download the PDB-style file with coordinates for d4hf4b_.
(The format of our PDB-style files is described here.)

Timeline for d4hf4b_: