SCOPe 2.06: Domain d4ef8b1: 4ef8 B:1-312

Lineage for d4ef8b1 (4ef8 B:1-312)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (18 species)
   not a true protein

7. Species Leishmania major [TaxId:5664] [255853] (6 PDB entries)

8. Domain d4ef8b1: 4ef8 B:1-312 [251740]
   Other proteins in same PDB: d4ef8a2, d4ef8b2
   automated match to d3c61a_
   complexed with 0fi, fmn, gol, so4

Details for d4ef8b1

PDB Entry: 4ef8, 1.56 Å

PDB Description: Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with Phenyl isothiocyanate

PDB Compounds: (B:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d4ef8b1:

Sequence; same for both SEQRES and ATOM records:

>d4ef8b1 c.1.4.1 (B:1-312) automated matches {Leishmania major [TaxId: 5664]}
mslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpryq
alplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaavate
kgvilelnlscpnvpgkpqvaydfdamrqcltavsevyphsfgvkmppyfdfahfdaaae
ilnefpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrr
cpgklifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryq
tldefrgkvrtl

Timeline for d4ef8b1:

• d4ef8b1 first appeared in SCOPe 2.04, called d4ef8b_
  
• d4ef8b1 was called d4ef8b_ in SCOPe 2.05
  
• d4ef8b1 appears in SCOPe 2.07
  
• d4ef8b1 appears in the current release, SCOPe 2.08