SCOPe 2.06: Domain d4e3xa1: 4e3x A:22-562

Lineage for d4e3xa1 (4e3x A:22-562)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (49 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [256133] (9 PDB entries)

8. Domain d4e3xa1: 4e3x A:22-562 [251653]
   Other proteins in same PDB: d4e3xa2, d4e3xb2
   automated match to d4oe5a_
   complexed with 16p, pge, pro

Details for d4e3xa1

PDB Entry: 4e3x, 1.24 Å

PDB Description: Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline

PDB Compounds: (A:) Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

SCOPe Domain Sequences for d4e3xa1:

Sequence; same for both SEQRES and ATOM records:

>d4e3xa1 c.82.1.0 (A:22-562) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
lrwkhtsslkvanepilafsqgsperdalqkalkdlkgqteaipcvvgdeevwtsdiqyq
lspfnhahkvakfcyadkallnraidaalaarkewdlkpmadraqvflkaadmlsgprra
evlaktmvgqgktviqaeidaaaelidffrfnakfavelegeqpisvppstnhtvyrgle
gfvaaispfnftaiggnlagapalmgnvvlwkpsdtamlasyavyrilreaglppniiqf
vpadgptfgdtvtssehlcginftgsvptfkhlwrqvaqnldrfrtfprlagecggknfh
fvhssadvdsvvsgtlrsafeyggqkcsacsrlyvpkslwpqikgrlleehsrikvgdpa
edfgtffsavidakafarikkwleharsspslsilaggqcnesvgyyvepciieskdpqe
pimkeeifgpvltvyvypddkyretlklvdsttsygltgavfaqdkaivqeatrmlrnaa
gnfyindkstgsvvgqqpfggarasgtndkpggphyilrwtspqvikethkplgdwrysy
m

Timeline for d4e3xa1:

• d4e3xa1 first appeared in SCOPe 2.04, called d4e3xa_
  
• d4e3xa1 was called d4e3xa_ in SCOPe 2.05
  
• d4e3xa1 appears in SCOPe 2.07
  
• d4e3xa1 appears in the current release, SCOPe 2.08