SCOPe 2.08: Domain d4e00a2: 4e00 A:186-374

Lineage for d4e00a2 (4e00 A:186-374)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain [69804] (3 proteins)

6. Protein Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) [69805] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [69806] (15 PDB entries)

8. Domain d4e00a2: 4e00 A:186-374 [251639]
   Other proteins in same PDB: d4e00a1
   automated match to d3tz0a2
   complexed with 0f1, adp, k, mg

Details for d4e00a2

PDB Entry: 4e00, 2.15 Å

PDB Description: Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with ADP

PDB Compounds: (A:) [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

SCOPe Domain Sequences for d4e00a2:

Sequence, based on SEQRES records:

>d4e00a2 d.122.1.4 (A:186-374) Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dfvgiictrlspkkiiekwvdfarrlcehkygnaprvringhvaarfpfipmpldyilpe
llknamratmeshldtpynvpdvvitianndvdliirisdrgggiahkdldrvmdyhftt
aeastqdprisplfghldmhsggqsgpmhgfgfglptsrayaeylggslqlqslqgigtd
vylrlrhid

Sequence, based on observed residues (ATOM records):

>d4e00a2 d.122.1.4 (A:186-374) Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dfvgiictrlspkkiiekwvdfarrlcehkygnaprvringhvaarfpfipmpldyilpe
llknamratmeshldtpynvpdvvitianndvdliirisdrgggiahkdldrvmdyhftt
agfgfglptsrayaeylggslqlqslqgigtdvylrlrhid

Timeline for d4e00a2:

• d4e00a2 first appeared in SCOPe 2.04
  
• d4e00a2 appears in SCOPe 2.07