Lineage for d4dw6a2 (4dw6 A:97-214)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2334734Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
    multihelical; interlocked (homo)dimer
  4. 2334735Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families) (S)
  5. 2334736Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 protein domains)
  6. 2334743Protein Ethr repressor [109978] (2 species)
  7. 2334744Species Mycobacterium tuberculosis [TaxId:1773] [109979] (43 PDB entries)
    Uniprot P96222 22-215
  8. 2334757Domain d4dw6a2: 4dw6 A:97-214 [251627]
    Other proteins in same PDB: d4dw6a1
    automated match to d3sfia2
    protein/DNA complex; complexed with 0mn, gol, nh4

Details for d4dw6a2

PDB Entry: 4dw6 (more details), 2 Å

PDB Description: Novel N-phenyl-phenoxyacetamide derivatives as potential EthR inhibitors and ethionamide boosters. Discovery and optimization using High-Throughput Synthesis.
PDB Compounds: (A:) HTH-type transcriptional regulator EthR

SCOPe Domain Sequences for d4dw6a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4dw6a2 a.121.1.1 (A:97-214) Ethr repressor {Mycobacterium tuberculosis [TaxId: 1773]}

SCOPe Domain Coordinates for d4dw6a2:

Click to download the PDB-style file with coordinates for d4dw6a2.
(The format of our PDB-style files is described here.)

Timeline for d4dw6a2:

View in 3D
Domains from same chain:
(mouse over for more information)