SCOPe 2.08: Domain d4dj9a2: 4dj9 A:129-254

Lineage for d4dj9a2 (4dj9 A:129-254)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (29 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.9: alpha-catenin/vinculin-like [47220] (2 families)

5. Family a.24.9.1: alpha-catenin/vinculin [47221] (3 proteins)
   possible duplication: contains several domains of this fold
   The listed PDB entries contain different large fragments but not the whole proteins

6. Protein Vinculin [47224] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101111] (16 PDB entries)
   Uniprot P18206 1-257

8. Domain d4dj9a2: 4dj9 A:129-254 [251461]
   automated match to d3rf3b2

Details for d4dj9a2

PDB Entry: 4dj9, 2.25 Å

PDB Description: Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)

PDB Compounds: (A:) vinculin

SCOPe Domain Sequences for d4dj9a2:

Sequence, based on SEQRES records:

>d4dj9a2 a.24.9.1 (A:129-254) Vinculin {Human (Homo sapiens) [TaxId: 9606]}
aevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqqelthqehr
vmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsaeineiirvl
qltswd

Sequence, based on observed residues (ATOM records):

>d4dj9a2 a.24.9.1 (A:129-254) Vinculin {Human (Homo sapiens) [TaxId: 9606]}
aevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqqelthqehr
vmlvnsmntvkellpvlisamkifvttqgieealknrnftvekmsaeineiirvlqltsw
d

Timeline for d4dj9a2:

• d4dj9a2 first appeared in SCOPe 2.04
  
• d4dj9a2 appears in SCOPe 2.07