SCOPe 2.08: Domain d4dbna_: 4dbn A:

Lineage for d4dbna_ (4dbn A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4dbna_: 4dbn A: [251396]
   automated match to d4e26a_
   complexed with 0ja

Details for d4dbna_

PDB Entry: 4dbn, 3.15 Å

PDB Description: Crystal Structure of the Kinase domain of Human B-raf with a [1,3]thiazolo[5,4-b]pyridine derivative

PDB Compounds: (A:) Serine/threonine-protein kinase B-raf

SCOPe Domain Sequences for d4dbna_:

Sequence, based on SEQRES records:

>d4dbna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglatvksrwsgshqfeqlsgsilwmapevirm
qdknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpk
amkrlmaeclkkkrderplfpqilasiellarsl

Sequence, based on observed residues (ATOM records):

>d4dbna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglgsilwmapevirmqdknpysfqsdvyafgi
vlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkkkrder
plfpqilasiellarsl

Timeline for d4dbna_:

• d4dbna_ first appeared in SCOPe 2.04
  
• d4dbna_ appears in SCOPe 2.07