Lineage for d4cbtb_ (4cbt B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2115321Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456
  4. 2115322Superfamily c.42.1: Arginase/deacetylase [52768] (3 families) (S)
  5. 2115600Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 protein domains)
    automatically mapped to Pfam PF00850
  6. 2115643Protein automated matches [190786] (1 species)
    not a true protein
  7. 2115644Species Human (Homo sapiens) [TaxId:9606] [188039] (33 PDB entries)
  8. 2115691Domain d4cbtb_: 4cbt B: [251360]
    Other proteins in same PDB: d4cbta2, d4cbtc2, d4cbtc3
    automated match to d4cbyd_
    complexed with 9f4, zn

Details for d4cbtb_

PDB Entry: 4cbt (more details), 3.03 Å

PDB Description: Design, synthesis, and biological evaluation of potent and selective Class IIa HDAC inhibitors as a potential therapy for Huntingtons disease
PDB Compounds: (B:) Histone deacetylase 4

SCOPe Domain Sequences for d4cbtb_:

Sequence, based on SEQRES records: (download)

>d4cbtb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kprfttglvydtlmlkhqctcgsssshpehagriqsiwsrlqetglrgkcecirgrkatl
eelqtvhseahtllygtnplnrqkldskkllgslasvfvrlpcggvgvdsdtiwnevhsa
gaarlavgcvvelvfkvatgelkngfavvrppghhaeestpmgfcyfnsvavaakllqqr
lsvskilivdwdvhhgngtqqafysdpsvlymslhryddgnffpgsgapdevgtgpgvgf
nvnmaftggldppmgdaeylaafrtvvmpiasefapdvvlvssgfdaveghptplggynl
sarcfgyltkqlmglaggrivlalegghdltaicdaseacvsallgneldplpekvlqqr
pnanavrsmekvmeihskywrclq

Sequence, based on observed residues (ATOM records): (download)

>d4cbtb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kprfttglvydtlmlkhqctcgsssshpehagriqsiwsrlqetglrgkcecirgrkatl
eelqtvhseahtllygtnpsdtiwnevhsagaarlavgcvvelvfkvatgelkngfavvr
ppghhaeestpmgfcyfnsvavaakllqqrlsvskilivdwdvhhgngtqqafysdpsvl
ymslhryddgnffpgsgapdevgtgpgvgfnvnmaftggldppmgdaeylaafrtvvmpi
asefapdvvlvssgfdaveghptplggynlsarcfgyltkqlmglaggrivlalegghdl
taicdaseacvsallgndplpekvlqqrpnanavrsmekvmeihskywrclq

SCOPe Domain Coordinates for d4cbtb_:

Click to download the PDB-style file with coordinates for d4cbtb_.
(The format of our PDB-style files is described here.)

Timeline for d4cbtb_: