SCOPe 2.05: Domain d4btka_: 4btk A:

Lineage for d4btka_ (4btk A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d4btka_: 4btk A: [251324]
   automated match to d4nfna_
   complexed with dms, dtq

Details for d4btka_

PDB Entry: 4btk, 2 Å

PDB Description: ttbk1 in complex with inhibitor

PDB Compounds: (A:) tau-tubulin kinase 1

SCOPe Domain Sequences for d4btka_:

Sequence, based on SEQRES records:

>d4btka_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dilpanyvvkdrwkvlkkiggggfgeiyeamdlltrenvalkvesaqqpkqvlkmevavl
kklqgkdhvcrfigcgrnekfnyvvmqlqgrnladlrrsqprgtftlsttlrlgkqiles
ieaihsvgflhrdikpsnfamgrlpstyrkcymldfglarqytnttgdvrpprnvagfrg
tvryasvnahknremgrhddlwslfymlvefavgqlpwrkikdkeqvgmikekyehrmll
khmpsefhlfldhiasldyftkpdyqlimsvfensmkergiaeneafdwe

Sequence, based on observed residues (ATOM records):

>d4btka_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dilpanyvvkdrwkvlkkigggeiyeamdlltrenvalkvesaqqpkqvlkmevavlkkl
qgkdhvcrfigcgrnekfnyvvmqlqgrnladlrrsqprgtftlsttlrlgkqilesiea
ihsvgflhrdikpsnfamgrlpstyrkcymldfglarqytnttgdvrpprnvagfrgtvr
yasvnahknremgrhddlwslfymlvefavgqlpwrkikdkeqvgmikekyehrmllkhm
psefhlfldhiasldyftkpdyqlimsvfensmkergiaeneafdwe

Timeline for d4btka_:

• d4btka_ first appeared in SCOPe 2.04
  
• d4btka_ appears in SCOPe 2.06
  
• d4btka_ appears in the current release, SCOPe 2.08