SCOPe 2.07: Domain d4bjob1: 4bjo B:2-280

Lineage for d4bjob1 (4bjo B:2-280)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein automated matches [190252] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187034] (47 PDB entries)

8. Domain d4bjob1: 4bjo B:2-280 [251268]
   Other proteins in same PDB: d4bjoa2, d4bjob2
   automated match to d1suga_
   complexed with cl, edo, mg, no3

Details for d4bjob1

PDB Entry: 4bjo, 2.06 Å

PDB Description: nitrate in the active site of ptp1b is a putative mimetic of the transition state

PDB Compounds: (B:) tyrosine-protein phosphatase non-receptor type 1

SCOPe Domain Sequences for d4bjob1:

Sequence; same for both SEQRES and ATOM records:

>d4bjob1 c.45.1.2 (B:2-280) automated matches {Human (Homo sapiens) [TaxId: 9606]}
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdp
ssvdikkvllemrkfrmgliqtadqlrfsylaviegakf

Timeline for d4bjob1:

• d4bjob1 first appeared in SCOPe 2.04, called d4bjob_
  
• d4bjob1 appears in SCOPe 2.06
  
• d4bjob1 appears in the current release, SCOPe 2.08