SCOPe 2.08: Domain d4bf2b_: 4bf2 B:

Lineage for d4bf2b_ (4bf2 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4bf2b_: 4bf2 B: [251229]
   automated match to d2qg5d_
   complexed with act, gol, stu

Details for d4bf2b_

PDB Entry: 4bf2, 2.11 Å

PDB Description: Crystal Structures of Ask1-inhibitor Complexes

PDB Compounds: (B:) mitogen-activated protein kinase kinase kinase 5

SCOPe Domain Sequences for d4bf2b_:

Sequence, based on SEQRES records:

>d4bf2b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
leydyeydengdrvvlgkgtygivyagrdlsnqvriaikeiperdsrysqplheeialhk
hlkhknivqylgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileg
lkylhdnqivhrdikgdnvlintysgvlkisdfgtskrlaginpcteeftgtlqymapei
idkgprgygkaadiwslgctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsae
akafilkcfepdpdkracandllvdeflkv

Sequence, based on observed residues (ATOM records):

>d4bf2b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
leydyeydengdrvvlgkgtygivyagrdlsnqvriaikeipereeialhkhlkhknivq
ylgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileglkylhdnqi
vhrdikgdnvlintysgvlkisdfgtskrlatgtlqymapeiidkgprgygkaadiwslg
ctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsaeakafilkcfepdpdkrac
andllvdeflkv

Timeline for d4bf2b_:

• d4bf2b_ first appeared in SCOPe 2.04
  
• d4bf2b_ appears in SCOPe 2.07