SCOPe 2.07: Domain d3tt1b_: 3tt1 B:

Lineage for d3tt1b_ (3tt1 B:)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein Na(+):neurotransmitter symporter homologue LeuT [161072] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [161073] (43 PDB entries)
   Uniprot O67854 5-513

8. Domain d3tt1b_: 3tt1 B: [250022]
   Other proteins in same PDB: d3tt1l1, d3tt1l2, d3tt1m1, d3tt1m2
   automated match to d2q6ha_
   complexed with na, sog

Details for d3tt1b_

PDB Entry: 3tt1, 3.1 Å

PDB Description: crystal structure of leut in the outward-open conformation in complex with fab

PDB Compounds: (B:) Leucine transporter LeuT

SCOPe Domain Sequences for d3tt1b_:

Sequence, based on SEQRES records:

>d3tt1b_ f.54.1.1 (B:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyfvyieswtlgfaikflv
glvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsili
rgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvw
iaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlneaaevilggsisipaava
ffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmi
afledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiff
wifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvw
itrfyiiglflfltflvflaerr

Sequence, based on observed residues (ATOM records):

>d3tt1b_ f.54.1.1 (B:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyfvyieswtlgfaikflv
glvpetdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgisk
gierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaavg
qifftlslgfgaiityasyvrkdqdivlsgltaatlneaaevilggsisipaavaffgva
navaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafled
elklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwifga
dkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwitrfy
iiglflfltflvflaerr

Timeline for d3tt1b_:

• d3tt1b_ first appeared in SCOPe 2.04
  
• d3tt1b_ appears in SCOPe 2.06
  
• d3tt1b_ appears in the current release, SCOPe 2.08