SCOPe 2.04: Domain d3trob_: 3tro B:

Lineage for d3trob_ (3tro B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (14 species)
   not a true protein

7. Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)

8. Domain d3trob_: 3tro B: [249995]
   automated match to d3c61a_
   complexed with fmn, gol, so4; mutant

Details for d3trob_

PDB Entry: 3tro, 1.86 Å

PDB Description: Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A

PDB Compounds: (B:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d3trob_:

Sequence, based on SEQRES records:

>d3trob_ c.1.4.1 (B:) automated matches {Leishmania major [TaxId: 347515]}
gsmslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpr
yqalplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaava
tekgvilelnlscpnvpgkpqvaydfdamrqcltavsevyphsfgvkmppyfafahfdaa
aeilnefpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafy
rrcpgklifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkr
yqtldefrgkvrtl

Sequence, based on observed residues (ATOM records):

>d3trob_ c.1.4.1 (B:) automated matches {Leishmania major [TaxId: 347515]}
gsmslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpr
yqalplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaava
tekgvilelnlspqvaydfdamrqcltavsevyphsfgvkmppyfafahfdaaaeilnef
pkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrrcpgkl
ifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryqtldef
rgkvrtl

Timeline for d3trob_:

• d3trob_ is new in SCOPe 2.04-stable
  
• d3trob_ appears in SCOPe 2.05
  
• d3trob_ appears in the current release, SCOPe 2.08, called d3trob1