Lineage for d3sdga2 (3sdg A:98-214)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2334734Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
    multihelical; interlocked (homo)dimer
  4. 2334735Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families) (S)
  5. 2334736Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 protein domains)
  6. 2334743Protein Ethr repressor [109978] (2 species)
  7. 2334744Species Mycobacterium tuberculosis [TaxId:1773] [109979] (45 PDB entries)
    Uniprot P96222 22-215
  8. 2334752Domain d3sdga2: 3sdg A:98-214 [249370]
    Other proteins in same PDB: d3sdga1
    automated match to d3sfia2
    protein/DNA complex; complexed with 3se

Details for d3sdga2

PDB Entry: 3sdg (more details), 1.87 Å

PDB Description: ethionamide boosters part 2: combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole ethr inhibitors.
PDB Compounds: (A:) HTH-type transcriptional regulator EthR

SCOPe Domain Sequences for d3sdga2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3sdga2 a.121.1.1 (A:98-214) Ethr repressor {Mycobacterium tuberculosis [TaxId: 1773]}

SCOPe Domain Coordinates for d3sdga2:

Click to download the PDB-style file with coordinates for d3sdga2.
(The format of our PDB-style files is described here.)

Timeline for d3sdga2:

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