SCOPe 2.08: Domain d3sckb_: 3sck B:

Lineage for d3sckb_ (3sck B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein Angiotensin converting enzyme 2, ACE2 [103125] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [103126] (34 PDB entries)

8. Domain d3sckb_: 3sck B: [249348]
   Other proteins in same PDB: d3scke_, d3sckf_
   automated match to d3d0ga_
   complexed with cl, zn

Details for d3sckb_

PDB Entry: 3sck, 3 Å

PDB Description: crystal structure of spike protein receptor-binding domain from a predicted sars coronavirus civet strain complexed with human-civet chimeric receptor ace2

PDB Compounds: (B:) Angiotensin-converting enzyme 2 chimera

SCOPe Domain Sequences for d3sckb_:

Sequence; same for both SEQRES and ATOM records:

>d3sckb_ d.92.1.5 (B:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stteelaktfletfnyeaqelsyqssvaswnyntniteenvqnmnnagdkwsaflkeqst
laqtyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

Timeline for d3sckb_:

• d3sckb_ first appeared in SCOPe 2.04
  
• d3sckb_ appears in SCOPe 2.07