SCOPe 2.07: Domain d3qfra2: 3qfr A:243-521

Lineage for d3qfra2 (3qfr A:243-521)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.43: Reductase/isomerase/elongation factor common domain [50412] (4 superfamilies)
   barrel, closed; n=6, S=10; greek-key

4. Superfamily b.43.4: Riboflavin synthase domain-like [63380] (4 families)

5. Family b.43.4.1: NADPH-cytochrome p450 reductase FAD-binding domain-like [50438] (4 proteins)
   there is an alpha-helical subdomain inserted in this domain
   automatically mapped to Pfam PF00667

6. Protein automated matches [227066] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [226187] (8 PDB entries)

8. Domain d3qfra2: 3qfr A:243-521 [248876]
   Other proteins in same PDB: d3qfra1, d3qfra3, d3qfrb1, d3qfrb3
   automated match to d1j9za1
   complexed with ca, fad, fmn, nap; mutant

Details for d3qfra2

PDB Entry: 3qfr, 2.4 Å

PDB Description: Crystal Structure of Human NADPH-Cytochrome P450 Reductase (R457H Mutant)

PDB Compounds: (A:) NADPH--cytochrome P450 reductase

SCOPe Domain Sequences for d3qfra2:

Sequence, based on SEQRES records:

>d3qfra2 b.43.4.1 (A:243-521) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
vvearrhilailqdcpslrppidhlcellprlqahyysiassskvhpnsvhicavvveye
tkagrinkgvatnwlrakepagenggralvpmfvrksqf

Sequence, based on observed residues (ATOM records):

>d3qfra2 b.43.4.1 (A:243-521) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
vvearrhilailqdcpslrppidhlcellprlqahyysiassskvhpnsvhicavvveye
tkagrinkgvatnwlrakepalvpmfvrksqf

Timeline for d3qfra2:

• d3qfra2 first appeared in SCOPe 2.04
  
• d3qfra2 appears in SCOPe 2.06
  
• d3qfra2 appears in the current release, SCOPe 2.08