Lineage for d3qara1 (3qar A:147-321)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2158219Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
  4. 2158220Superfamily d.15.1: Ubiquitin-like [54236] (11 families) (S)
  5. 2159292Family d.15.1.5: Ras-binding domain, RBD [54263] (14 protein domains)
    contains Pfam PF00788 and Pfam PF02196
  6. 2159312Protein Phoshoinositide 3-kinase (PI3K) [54274] (2 species)
    includes parts of the flanking linkers
  7. 2159313Species Human (Homo sapiens) [TaxId:9606] [54276] (65 PDB entries)
  8. 2159337Domain d3qara1: 3qar A:147-321 [248830]
    Other proteins in same PDB: d3qara2, d3qara3, d3qara4
    automated match to d1e7ua3
    complexed with qar, so4

Details for d3qara1

PDB Entry: 3qar (more details), 2.65 Å

PDB Description: Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 32
PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d3qara1:

Sequence, based on SEQRES records: (download)

>d3qara1 d.15.1.5 (A:147-321) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
sqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskp
lpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqs
eqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrke

Sequence, based on observed residues (ATOM records): (download)

>d3qara1 d.15.1.5 (A:147-321) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
sqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskp
lpeylwkkianncifivihrsttsqtikvspddtpgailqsfdfvlrvcgrdeylvgetp
iknfqwvrhclkngeeihvvldtppdpaldevrke

SCOPe Domain Coordinates for d3qara1:

Click to download the PDB-style file with coordinates for d3qara1.
(The format of our PDB-style files is described here.)

Timeline for d3qara1: