Lineage for d3lzbb_ (3lzb B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2546221Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2546222Protein automated matches [190417] (29 species)
    not a true protein
  7. 2546365Species Human (Homo sapiens) [TaxId:9606] [187294] (1137 PDB entries)
  8. 2547197Domain d3lzbb_: 3lzb B: [247561]
    automated match to d2r4ba_
    complexed with iti

Details for d3lzbb_

PDB Entry: 3lzb (more details), 2.7 Å

PDB Description: EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor
PDB Compounds: (B:) Epidermal growth factor receptor

SCOPe Domain Sequences for d3lzbb_:

Sequence, based on SEQRES records: (download)

>d3lzbb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
llrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeilde
ayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqia
kgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpikwma
lesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictid
vymimrkcwmidadsrpkfreliiefskmardpqrylviqg

Sequence, based on observed residues (ATOM records): (download)

>d3lzbb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
llrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeilde
ayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqia
kgmnyledrrlvhrdlaarnvlvktpqhvkitdfglkvpikwmalesilhriythqsdvw
sygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimrkcwmidadsr
pkfreliiefskmardpqrylviqg

SCOPe Domain Coordinates for d3lzbb_:

Click to download the PDB-style file with coordinates for d3lzbb_.
(The format of our PDB-style files is described here.)

Timeline for d3lzbb_: