Lineage for d3lg4a_ (3lg4 A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477520Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2477899Protein automated matches [190514] (11 species)
    not a true protein
  7. 2477929Species Staphylococcus aureus [TaxId:1280] [195885] (5 PDB entries)
  8. 2477936Domain d3lg4a_: 3lg4 A: [247454]
    automated match to d4fgga_
    complexed with 52v, ndp; mutant

Details for d3lg4a_

PDB Entry: 3lg4 (more details), 3.15 Å

PDB Description: Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d3lg4a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3lg4a_ c.71.1.1 (A:) automated matches {Staphylococcus aureus [TaxId: 1280]}

SCOPe Domain Coordinates for d3lg4a_:

Click to download the PDB-style file with coordinates for d3lg4a_.
(The format of our PDB-style files is described here.)

Timeline for d3lg4a_: