SCOPe 2.08: Domain d3kswa_: 3ksw A:

Lineage for d3kswa_ (3ksw A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (99 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:5693] [196511] (20 PDB entries)

8. Domain d3kswa_: 3ksw A: [247268]
   automated match to d3khma_
   complexed with hem, vnf

Details for d3kswa_

PDB Entry: 3ksw, 3.05 Å

PDB Description: crystal structure of sterol 14alpha-demethylase (cyp51) from trypanosoma cruzi in complex with an inhibitor vnf ((4-(4- chlorophenyl)-n-[2-(1h-imidazol-1-yl)-1-phenylethyl]benzamide)

PDB Compounds: (A:) Sterol 14-alpha demethylase

SCOPe Domain Sequences for d3kswa_:

Sequence, based on SEQRES records:

>d3kswa_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ktppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllkav
yrdgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaq
lnydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshh
deeafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllr
devpdpdyhtmvvgptlnqclvkytrkk

Sequence, based on observed residues (ATOM records):

>d3kswa_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ktppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmplplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllkavyrdg
trmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnyd
nvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeea
fpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevp
dpdyhtmvvgptlnqclvkytrkk

Timeline for d3kswa_:

• d3kswa_ first appeared in SCOPe 2.04
  
• d3kswa_ appears in SCOPe 2.07