SCOPe 2.06: Domain d3krxa1: 3krx A:30-185

Lineage for d3krxa1 (3krx A:30-185)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.91: Regulator of G-protein signaling, RGS [48096] (1 superfamily)
   multihelical; consists of two all-alpha subdomains
   contains a 4-helical bundle with left-handed twist and up-and-down topology

4. Superfamily a.91.1: Regulator of G-protein signaling, RGS [48097] (2 families)

5. Family a.91.1.0: automated matches [191379] (1 protein)
   not a true family

6. Protein automated matches [190464] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187381] (30 PDB entries)

8. Domain d3krxa1: 3krx A:30-185 [247255]
   Other proteins in same PDB: d3krxa2, d3krxa3, d3krxb_, d3krxg_
   automated match to d1omwa1
   complexed with ba1, mg

Details for d3krxa1

PDB Entry: 3krx, 3.1 Å

PDB Description: Human GRK2 in complex with Gbetgamma subunits and balanol (co-crystal)

PDB Compounds: (A:) Beta-adrenergic receptor kinase 1

SCOPe Domain Sequences for d3krxa1:

Sequence, based on SEQRES records:

>d3krxa1 a.91.1.0 (A:30-185) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclnhleearplvefyeei
kkyekleteeervarsreifdsyimkellacshpfsksatehvqghlgkkqvppdlfqpy
ieeicqnlrgdvfqkfiesdkftrfcqwknvelnih

Sequence, based on observed residues (ATOM records):

>d3krxa1 a.91.1.0 (A:30-185) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclnhleearplvefyeei
kkyekleteeervarsreifdsyimkellahpfsksatehvqghlgkkqvppdlfqpyie
eicqnlrgdvfqkfiesdkftrfcqwknvelnih

Timeline for d3krxa1:

• d3krxa1 first appeared in SCOPe 2.04
  
• d3krxa1 appears in SCOPe 2.05
  
• d3krxa1 appears in SCOPe 2.07
  
• d3krxa1 appears in the current release, SCOPe 2.08