SCOPe 2.06: Domain d1adga1: 1adg A:1-163,A:340-374

Lineage for d1adga1 (1adg A:1-163,A:340-374)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.35: GroES-like [50128] (2 superfamilies)
   contains barrel, partly opened; n*=4, S*=8; meander

4. Superfamily b.35.1: GroES-like [50129] (3 families)

5. Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain [50136] (15 proteins)
   C-terminal domain is alpha/beta (classical Rossmann-fold)

6. Protein Alcohol dehydrogenase [50137] (9 species)
   contains a Zn-finger subdomain, residues 94-117

7. Species Horse (Equus caballus) [TaxId:9796] [50138] (46 PDB entries)
   Uniprot P00327

8. Domain d1adga1: 1adg A:1-163,A:340-374 [24700]
   Other proteins in same PDB: d1adga2
   complexed with sad, zn

Details for d1adga1

PDB Entry: 1adg, 2.7 Å

PDB Description: crystallographic studies of two alcohol dehydrogenase-bound analogs of thiazole-4-carboxamide adenine dinucleotide (tad), the active anabolite of the antitumor agent tiazofurin

PDB Compounds: (A:) alcohol dehydrogenase

SCOPe Domain Sequences for d1adga1:

Sequence; same for both SEQRES and ATOM records:

>d1adga1 b.35.1.2 (A:1-163,A:340-374) Alcohol dehydrogenase {Horse (Equus caballus) [TaxId: 9796]}
stagkvikckaavlweekkpfsieevevappkahevrikmvatgicrsddhvvsgtlvtp
lpviagheaagivesigegvttvrpgdkviplftpqcgkcrvckhpegnfclkndlsmpr
gtmqdgtsrftcrgkpihhflgtstfsqytvvdeisvakidaaXfaldplithvlpfeki
negfdllrsgesirtiltf

Timeline for d1adga1:

• d1adga1 first appeared (with stable ids) in SCOP 1.55, called d1adg_1
  
• d1adga1 appears in SCOPe 2.05
  
• d1adga1 appears in SCOPe 2.07
  
• d1adga1 appears in the current release, SCOPe 2.08