SCOPe 2.06: Domain d3hqza_: 3hqz A:

Lineage for d3hqza_ (3hqz A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (9 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [255521] (11 PDB entries)

8. Domain d3hqza_: 3hqz A: [246526]
   automated match to d4lm1a_
   complexed with mg, pf8, so4, zn

Details for d3hqza_

PDB Entry: 3hqz, 1.7 Å

PDB Description: Discovery of novel inhibitors of PDE10A

PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d3hqza_:

Sequence; same for both SEQRES and ATOM records:

>d3hqza_ a.211.1.0 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
nlparicrdielfhfdigpfenmwpgifvymihrscgtscfeleklcrfimsvkknyrrv
pyhnwkhavtvahcmyailqnnnglftdlerkglliaclchdldhrgfsnsylqkfdhpl
aalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnr
kqleemyqtgslnlhnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegde
mkklgiqpipmmdrdkrdevpqgqlgfynavaipcyttltqilpptepllkacrdnlnqw
ekvir

Timeline for d3hqza_:

• d3hqza_ first appeared in SCOPe 2.04
  
• d3hqza_ appears in SCOPe 2.05
  
• d3hqza_ appears in SCOPe 2.07
  
• d3hqza_ appears in the current release, SCOPe 2.08