SCOPe 2.07: Domain d3hmpa_: 3hmp A:

Lineage for d3hmpa_ (3hmp A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d3hmpa_: 3hmp A: [246513]
   automated match to d4jt3a_
   complexed with 7pe, cx4, gol, ipa, peg

Details for d3hmpa_

PDB Entry: 3hmp, 2.3 Å

PDB Description: Crystal structure of human Mps1 catalytic domain in complex with a quinazolin ligand Compound 4

PDB Compounds: (A:) Dual specificity protein kinase TTK

SCOPe Domain Sequences for d3hmpa_:

Sequence, based on SEQRES records:

>d3hmpa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnymppeai
kdmsssrengkskskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnheie
fpdipekdlqdvlkcclkrdpkqrisipellahpyvqiq

Sequence, based on observed residues (ATOM records):

>d3hmpa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmsqvgtvnymppeaikdmkispksd
vwslgcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdp
kqrisipellahpyvqiq

Timeline for d3hmpa_:

• d3hmpa_ first appeared in SCOPe 2.04
  
• d3hmpa_ appears in SCOPe 2.06
  
• d3hmpa_ appears in the current release, SCOPe 2.08