SCOPe 2.06: Domain d3hlvb_: 3hlv B:

Lineage for d3hlvb_ (3hlv B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d3hlvb_: 3hlv B: [246505]
   automated match to d3q95b_
   protein/DNA complex; complexed with j2z

Details for d3hlvb_

PDB Entry: 3hlv, 3 Å

PDB Description: crystal structure of human estrogen receptor alpha ligand-binding domain in complex with a glucocorticoid receptor interacting protein 1 nr box ii peptide and 16-alpha-hydroxy-estrone ((8s,9r,13s,14r, 16r)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6h- cyclopenta[a]phenanthren-17-one

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d3hlvb_:

Sequence, based on SEQRES records:

>d3hlvb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkit
dtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllem
ldahr

Sequence, based on observed residues (ATOM records):

>d3hlvb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsleekdhihrvldkitdtlih
lmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahr

Timeline for d3hlvb_:

• d3hlvb_ first appeared in SCOPe 2.04
  
• d3hlvb_ appears in SCOPe 2.05
  
• d3hlvb_ appears in SCOPe 2.07
  
• d3hlvb_ appears in the current release, SCOPe 2.08