SCOPe 2.06: Domain d3gb8a_: 3gb8 A:

Lineage for d3gb8a_ (3gb8 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (26 families)

5. Family a.118.1.19: Exportin HEAT-like repeat [117002] (2 proteins)
   Pfam PF08389, Pfam PF08767; full length proteins have several extra helices at C-terminus
   this is a repeat family; one repeat unit is 3gb8 A:533-577 found in domain

6. Protein Exportin-1 (Xpo1, Crm1) [117003] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [117004] (2 PDB entries)
   Uniprot O14980 707-1027

8. Domain d3gb8a_: 3gb8 A: [246276]
   Other proteins in same PDB: d3gb8b1, d3gb8b2, d3gb8b3
   protein/RNA complex

Details for d3gb8a_

PDB Entry: 3gb8, 2.9 Å

PDB Description: crystal structure of crm1/snurportin-1 complex

PDB Compounds: (A:) Exportin-1

SCOPe Domain Sequences for d3gb8a_:

Sequence, based on SEQRES records:

>d3gb8a_ a.118.1.19 (A:) Exportin-1 (Xpo1, Crm1) {Human (Homo sapiens) [TaxId: 9606]}
lkehpdawtrvdtilefsqnmntkyyglqilenviktrwkilprnqcegikkyvvgliik
tssdptcvekekvyigklnmilvqilkqewpkhwptfisdivgasrtseslcqnnmvilk
llseevfdfssgqitqvkskhlkdsmcnefsqifqlcqfvmensqnaplvhatletllrf
lnwiplgyifetklistliykflnvpmfrnvslkclteiagvsvsqyeeqfvtlftltmm
qlkqmlplntnirlaysngkddeqnfiqnlslflctflkehdqliekrlnlretlmealh
ymllvseveeteifkicleywnhlaaelyrespfstsaspllsgsqhfdvpprrqlylpm
lfkvrllmvsrmakpeevlvvendqgevvrefmkdtdsinlyknmretlvylthldyvdt
erimteklhnqvngtewswknlntlcwaigsisgamheedekrflvtvikdllglceqkr
gkdnkaiiasnimyivgqyprflrahwkflktvvnklfefmhethdgvqdmacdtfikia
qkcrrhfvqvqvgevmpfideilnnintiicdlqpqqvhtfyeavgymigaqtdqtvqeh
liekymllpnqvwdsiiqqatknvdilkdpetvkqlgsilktnvrackavghpfviqlgr
iyldmlnvykclsenisaaiqangemvtkqplirsmrtvkretlklisgwvsrsndpqmv
aenfvpplldavlidyqrnvpaarepevlstmaiivnklgghitaeipqifdavfectln
minkdfeeypehrtnfflllqavnshcfpaflaipptqfklvldsiiwafkhtmrnvadt
glqilftllqnvaqeeaaaqsfyqtyfcdilqhifsvvtdtshtagltmhasilaymfnl
veegkistslnpgnpvnnqiflqeyvanllksafphlqdaqvklfvtglfslnqdipafk
ehlrdflvqikefagedtsdlfleereialrqadeekhkrqmsvpgifnp

Sequence, based on observed residues (ATOM records):

>d3gb8a_ a.118.1.19 (A:) Exportin-1 (Xpo1, Crm1) {Human (Homo sapiens) [TaxId: 9606]}
lkehprvdtilefsqnmntkyyglqilenviktrwrnqcegikkyvvgliiktssekekv
yigklnmilvqilkqewpkhwptfisdivgasrtseslcqnnmvilkllseevftqvksk
hlkdsmcnefsqifqlcqfvmensqnaplvhatletllrflnwiplgyifetklistliy
kflnvpmfrnvslkclteiagvsvsqyeeqfvtlftltmmqlkqmlplntnirlaysngk
ddeqnfiqnlslflctflkehdqliekrlnlretlmealhymllvseveeteifkicley
wnhlaaelyrespfsvpprrqlylpmlfkvrllmvsrmakpeedtdsinlyknmretlvy
lthldyvdterimteklhnqvngtewswknlntlcwaigsisgamheedekrflvtvikd
llglceqkrgkdnkaiiasnimyivgqyprflrahwkflktvvnklfefmhethdgvqdm
acdtfikiaqkcrrhfvqvqvgevmpfideilnnintiicdlqpqqvhtfyeavgymiga
qtdqtvqehliekymllpnqvwdsiiqqatknvdilkdpetvkqlgsilktnvrackavg
hpfviqlgriyldmlnvykclsenisaaiqangemvtkqplirsmrtvkretlklisgwv
srsndpqmvaenfvpplldavlidyqrnvpaarepevlstmaiivnklgghitaeipqif
davfectlnminkdfeeypehrtnfflllqavnshcfpaflaipptqfklvldsiiwafk
htmrnvadtglqilftllqnvaqeeaaaqsfyqtyfcdilqhifsvvtdtshtagltmha
silaymfnlveegkistslnpgnpvnnqiflqeyvanllksafphlqdaqvklfvtglfs
lnqdipafkehlrdflvqikefagedtsdlfleereialrqadeekhkrqmsvpgifnp

Timeline for d3gb8a_:

• d3gb8a_ first appeared in SCOPe 2.04
  
• d3gb8a_ appears in SCOPe 2.05
  
• d3gb8a_ appears in SCOPe 2.07
  
• d3gb8a_ appears in the current release, SCOPe 2.08