SCOPe 2.07: Domain d3exgv2: 3exg V:192-329

Lineage for d3exgv2 (3exg V:192-329)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (5 proteins)
   automatically mapped to Pfam PF02780

6. Protein E1-beta subunit of pyruvate dehydrogenase, C-domain [69521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89713] (9 PDB entries)

8. Domain d3exgv2: 3exg V:192-329 [245981]
   Other proteins in same PDB: d3exg11, d3exg12, d3exg21, d3exg31, d3exg32, d3exg41, d3exg51, d3exg52, d3exg61, d3exga1, d3exga2, d3exgb1, d3exgc1, d3exgc2, d3exgd1, d3exge1, d3exge2, d3exgf1, d3exgg1, d3exgg2, d3exgh1, d3exgi1, d3exgi2, d3exgj1, d3exgk1, d3exgk2, d3exgl1, d3exgm1, d3exgm2, d3exgn1, d3exgo1, d3exgo2, d3exgp1, d3exgq1, d3exgq2, d3exgr1, d3exgs_, d3exgt1, d3exgu1, d3exgu2, d3exgv1, d3exgw1, d3exgw2, d3exgx1, d3exgy1, d3exgy2, d3exgz1
   automated match to d2ozlb2
   complexed with k

Details for d3exgv2

PDB Entry: 3exg, 3.01 Å

PDB Description: crystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex

PDB Compounds: (V:) Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

SCOPe Domain Sequences for d3exgv2:

Sequence; same for both SEQRES and ATOM records:

>d3exgv2 c.48.1.2 (V:192-329) E1-beta subunit of pyruvate dehydrogenase, C-domain {Human (Homo sapiens) [TaxId: 9606]}
lipigkakierqgthitvvshsrpvghcleaaavlskegvecevinmrtirpmdmetiea
svmktnhlvtveggwpqfgvgaeicarimegpafnfldapavrvtgadvpmpyakiledn
sipqvkdiifaikktlni

Timeline for d3exgv2:

• d3exgv2 first appeared in SCOPe 2.04
  
• d3exgv2 appears in SCOPe 2.06
  
• d3exgv2 appears in the current release, SCOPe 2.08