SCOPe 2.05: Domain d3exfb2: 3exf B:192-329

Lineage for d3exfb2 (3exf B:192-329)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (5 proteins)
   automatically mapped to Pfam PF02780

6. Protein E1-beta subunit of pyruvate dehydrogenase, C-domain [69521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89713] (7 PDB entries)

8. Domain d3exfb2: 3exf B:192-329 [245930]
   Other proteins in same PDB: d3exfa_, d3exfb1, d3exfc_, d3exfd1, d3exfe_, d3exff1, d3exfg_, d3exfh1
   automated match to d2ozlb2
   complexed with k, mg, tpp

Details for d3exfb2

PDB Entry: 3exf, 3 Å

PDB Description: crystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex

PDB Compounds: (B:) Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

SCOPe Domain Sequences for d3exfb2:

Sequence; same for both SEQRES and ATOM records:

>d3exfb2 c.48.1.2 (B:192-329) E1-beta subunit of pyruvate dehydrogenase, C-domain {Human (Homo sapiens) [TaxId: 9606]}
lipigkakierqgthitvvshsrpvghcleaaavlskegvecevinmrtirpmdmetiea
svmktnhlvtveggwpqfgvgaeicarimegpafnfldapavrvtgadvpmpyakiledn
sipqvkdiifaikktlni

Timeline for d3exfb2:

• d3exfb2 first appeared in SCOPe 2.04
  
• d3exfb2 appears in SCOPe 2.06
  
• d3exfb2 appears in the current release, SCOPe 2.08