SCOPe 2.05: Domain d3eo1i_: 3eo1 I:

Lineage for d3eo1i_ (3eo1 I:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein TGF-beta3 [57508] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57509] (5 PDB entries)

8. Domain d3eo1i_: 3eo1 I: [245893]
   Other proteins in same PDB: d3eo1a1, d3eo1a2, d3eo1d1, d3eo1d2, d3eo1g1, d3eo1g2, d3eo1j1, d3eo1j2
   automated match to d1tgja_

Details for d3eo1i_

PDB Entry: 3eo1, 3.1 Å

PDB Description: Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3

PDB Compounds: (I:) Transforming growth factor beta-3

SCOPe Domain Sequences for d3eo1i_:

Sequence; same for both SEQRES and ATOM records:

>d3eo1i_ g.17.1.2 (I:) TGF-beta3 {Human (Homo sapiens) [TaxId: 9606]}
aldtnycfrnleenccvrplyidfrqdlgwkwvhepkgyyanfcsgpcpylrsadtthst
vlglyntlnpeasaspccvpqdlepltilyyvgrtpkveqlsnmvvksckcs

Timeline for d3eo1i_:

• d3eo1i_ first appeared in SCOPe 2.04
  
• d3eo1i_ appears in SCOPe 2.06
  
• d3eo1i_ appears in the current release, SCOPe 2.08