Lineage for d3apca2 (3apc A:357-521)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2772794Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 2772795Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (4 families) (S)
    two constituent families are related by circular permutation
  5. 2772796Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)
  6. 2772819Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)
  7. 2772820Species Human (Homo sapiens) [TaxId:9606] [49572] (70 PDB entries)
  8. 2772830Domain d3apca2: 3apc A:357-521 [245173]
    Other proteins in same PDB: d3apca1, d3apca3, d3apca4
    automated match to d1e8wa2
    complexed with mmd, so4

Details for d3apca2

PDB Entry: 3apc (more details), 2.54 Å

PDB Description: Crystal structure of human PI3K-gamma in complex with CH5132799
PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d3apca2:

Sequence, based on SEQRES records: (download)

>d3apca2 b.7.1.1 (A:357-521) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
cdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllr
rgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilld

Sequence, based on observed residues (ATOM records): (download)

>d3apca2 b.7.1.1 (A:357-521) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
cdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycvqllyyvnlllidhrfllrrgeyvlhmwqisgfnadkltsa
tnpdkensmsisilld

SCOPe Domain Coordinates for d3apca2:

Click to download the PDB-style file with coordinates for d3apca2.
(The format of our PDB-style files is described here.)

Timeline for d3apca2: