SCOPe 2.05: Domain d2zi9b_: 2zi9 B:

Lineage for d2zi9b_ (2zi9 B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Deoxycytidine kinase [89657] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89658] (41 PDB entries)

8. Domain d2zi9b_: 2zi9 B: [244939]
   automated match to d1p60a_
   complexed with adp, cl9

Details for d2zi9b_

PDB Entry: 2zi9, 2.51 Å

PDB Description: c4s-e247a dck variant of dck in complex with cladribine+adp

PDB Compounds: (B:) Deoxycytidine kinase

SCOPe Domain Sequences for d2zi9b_:

Sequence, based on SEQRES records:

>d2zi9b_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
trikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqstqdefeeltmsqkng
gnvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifa
snlyesesmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeq
gipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyaslvekvkefls
tl

Sequence, based on observed residues (ATOM records):

>d2zi9b_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
trikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqnggnvlqmmyekperw
sftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesesmnetew
tiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykh
eswllhrtlktnfdylqevpiltldvnedfkdkyaslvekvkeflstl

Timeline for d2zi9b_:

• d2zi9b_ first appeared in SCOPe 2.04
  
• d2zi9b_ appears in SCOPe 2.06
  
• d2zi9b_ appears in the current release, SCOPe 2.08