SCOPe 2.08: Domain d2zdxb1: 2zdx B:20-187

Lineage for d2zdxb1 (2zdx B:20-187)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.5: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (2 families)
   automatically mapped to Pfam PF10436

5. Family a.29.5.0: automated matches [230678] (1 protein)
   not a true family

6. Protein automated matches [230679] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [230680] (8 PDB entries)

8. Domain d2zdxb1: 2zdx B:20-187 [244910]
   Other proteins in same PDB: d2zdxa2, d2zdxb2
   automated match to d2e0ab1
   complexed with p4a

Details for d2zdxb1

PDB Entry: 2zdx, 2.54 Å

PDB Description: Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4

PDB Compounds: (B:) Pyruvate dehydrogenase kinase isozyme 4

SCOPe Domain Sequences for d2zdxb1:

Sequence, based on SEQRES records:

>d2zdxb1 a.29.5.0 (B:20-187) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilptql
vntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgii
eykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgn

Sequence, based on observed residues (ATOM records):

>d2zdxb1 a.29.5.0 (B:20-187) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilptql
vtssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiey
kdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdqtgn

Timeline for d2zdxb1:

• d2zdxb1 first appeared in SCOPe 2.04
  
• d2zdxb1 appears in SCOPe 2.07