Lineage for d2xywb_ (2xyw B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008476Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2008477Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2008478Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2009403Protein automated matches [190059] (14 species)
    not a true protein
  7. 2009425Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)
  8. 2009633Domain d2xywb_: 2xyw B: [244641]
    automated match to d3ty0a_
    complexed with 08s, bog

Details for d2xywb_

PDB Entry: 2xyw (more details), 3.14 Å

PDB Description: novel sulfonylthiadiazoles with an unusual binding mode as partial dual peroxisome proliferator-activated receptor (ppar) gamma-delta agonists with high potency and in-vivo efficacy
PDB Compounds: (B:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d2xywb_:

Sequence, based on SEQRES records: (download)

>d2xywb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlvn
glppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifam
lasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfia
aiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteh
aqmmqrikktetetslhpllqeiykdm

Sequence, based on observed residues (ATOM records): (download)

>d2xywb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsiltgkapfvihdietlwqaekglvwkqlvnglpp
ykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasi
vnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiil
cgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmm
qrikktetetslhpllqeiykdm

SCOPe Domain Coordinates for d2xywb_:

Click to download the PDB-style file with coordinates for d2xywb_.
(The format of our PDB-style files is described here.)

Timeline for d2xywb_: